Just as the other two have already stated, space is a big issue. Also, batteries. Wind & solar energy are not available everywhere in the US and around the world. It can only be very effective in certain areas (like the Southwest for solar and Midwest and Appalachian Mountain Chain for wind). There currently is not an efficient way to store and transport energy to other parts of the nation/world.
So, in addition to what everyone else has said so far, I would say that the industry’s biggest hurdle is focusing primarily on wind and solar. They should be looking at biomass, hydrokynetic, and other forms, as well. Did you know cow manure (a form of biomass) can be processed to use the methane as a source of energy (like natural gas… It is natural, and it is a gas). The by-product of the process is smelly-free fertilizer! Farmers that have used the method on their dairy farms are churning out so much electricity into the grid, their entire farms run on it AND they get money from the power companies that service their area.
Hydrokynetic is relatively new to the industry. Basically, it’s the equivalent of putting huge turbines under large bodies of water to use the energy of the currents to create electricity.